KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Primary Antibodies
polyclonal
human,mouse,rat
Vascular endothelial growth factor receptor 2
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC, WB,FC
200 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:1000; IHC: 1:50-1:500
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
KDR
CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2
This product is for research use only.
Precio a consultar
Ver másPrecio a consultar
Ver másPrecio a consultar
Ver más