anti- ULK1 antibody

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935106861
info@markelab.com
name
anti- ULK1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09251
tested applications
ELISA, WB,IHC

Description

ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

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Product specifications

CategoryPrimary Antibodies
Immunogen Targetunc-51-like kinase 1(C. elegans)
HostRabbit
Reactivityhuman,rat
Recommended DilutionWB: 1:200-1:1000; IHC: 1:50-1:500
Clonalitypolyclonal
ConjugationUnconjugated
IsotypeIgG
Observed MW150 kDa
Purity≥95% as determined by SDS-PAGE
PurificationImmunogen affinity purified
Size 1100µg
Formliquid
Tested ApplicationsELISA, WB,IHC
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt IDO75385
Gene ID8408
AliasATG1, FLJ38455, FLJ46475, KIAA0722, ULK1, Unc 51 like kinase 1, UNC51, Unc51.1
BackgroundAntibody anti-ULK1
StatusRUO
NoteThis product is for research use only.

Descripción

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FNab09251

anti- ULK1 antibody

ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

Ver Producto