UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).
Primary Antibodies
polyclonal
human,mouse,rat
ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC, IP
26 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:5000; IHC:1:100-1:500; IP: 1:1000-1:5000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UCHL1
HEL-117,HEL-S-53,NDGOA,PARK5 PGP 9.5,PGP9.5,PGP95,SPG79,SPG79A,UCHL-1 Uch-L1,Neuron cytoplasmic protein 9.5,Ubiquitin thioesterase L1
This product is for research use only.
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