Name: anti- Tie2 antibody
Brand: FineTest
SKU: FNab08690
Availability: OnlineOnly

Descripción

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

TEK tyrosine kinase, endothelial

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF

observerd MW

126kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

TEK

alias

Angiopoietin-1 receptor,Endothelial tyrosine kinase,TIE2,VMCM,GLC3E,TIE-2,VMCM1,CD202B,Tyrosine-protein kinase receptor TEK,Tunica interna endothelial cell kinase

uniprot id

https://www.uniprot.org/uniprotkb/Q02763

gene id

https://www.ncbi.nlm.nih.gov/gene/7010

note

This product is for research use only.

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proveedor

FineTest

reference

EM0305

reactivity

mouse

status

RUO

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