TFIP11 antibody

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Description
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tuftelin interacting protein 11 (TFIP11) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:50-1:500 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 3H5 |
| Observed MW | 97 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UBB9 |
| Gene ID | 24144 |
| Alias | Tuftelin-interacting protein 11,Septin and tuftelin-interacting protein 1 (STIP-1),TFIP11,STIP |
| Background | Antibody anti-TFIP11 |
| Status | RUO |
| Note | Mol. Weight 97 kDa |
Descripción
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TFIP11 antibody
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
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