SIRT7 antibody

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Description
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sirtuin (silent mating type information regulation 2 homolog) 7 (SIRT7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NRC8 |
| Gene ID | 51547 |
| Alias | NAD-dependent protein deacetylase sirtuin-7,NAD-dependent protein deacylase sirtuin-7,Regulatory protein SIR2 homolog 7,SIR2-like protein 7,SIRT7,SIR2L7 |
| Background | Antibody anti-SIRT7 |
| Status | RUO |
| Note | Mol. Weight 45 kDa |
Descripción
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