SERPINI2 antibody

Este producto es parte de SERPINI2 - serpin family I member 2
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935106861
info@markelab.com
name
SERPINI2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07754
tested applications
ELISA, WB

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
serpin peptidase inhibitor, clade I(pancpin), member 2 (SERPINI2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
55 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O75830
Gene ID
5276
Alias
MEPI,PI14,PANCPIN,TSA2004,Serpin I2,Myoepithelium-derived serine protease inhibitor,Pancpin,Peptidase inhibitor 14
Background
Antibody anti-SERPINI2
Status
RUO
Note
Mol. Weight 55 kDa

SERPINI2 is a member of the serine protease inhibitor (serpin) family and is encoded by the SERPINI2 gene located on chromosome 3. The serpin superfamily comprises a large group of proteins that inhibit proteolytic enzymes, playing crucial roles in various biological processes such as blood coagulation, fibrinolysis, immune response, and tissue remodeling. Like other serpins, SERPINI2 regulates the activity of proteases by acting as a suicide substrate, forming a stable complex with the target protease, which leads to its irreversible inhibition. Although SERPINI2 is not as well-studied as other members of the serpin family, recent studies suggest that it is involved in the regulation of proteolysis in various tissues, with significant expression observed in pancreatic, hepatic, and other glandular tissues.

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