anti- SEMA3C antibody
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Precio
Precio a consultar
Antibody anti-SEMA3C
proveedor
FineTestreference
FNab07706Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance(By similarity).
Background
SEMA3C (Semaphorin 3C) is another key member of the class 3 semaphorins, primarily involved in neuronal pathfinding, cardiovascular development, and cancer biology. SEMA3C signals through neuropilin-2 (NRP2) and plexin receptors to regulate cellular behaviors such as migration, invasion, and adhesion. In cancer, SEMA3C is frequently upregulated, where it promotes tumor growth and metastasis by facilitating angiogenesis and modulating the tumor microenvironment. Its dual roles in development and oncogenesis make it a compelling target for both regenerative medicine and oncology.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
sema domain, immunoglobulin domain(Ig), short basic domain, secreted,(semaphorin) 3C
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB
observerd MW
70 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
SEMA3C
alias
SemE,SEMAE,Semaphorin-E
uniprot id
note
This product is for research use only.
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