RSPO2 antibody
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935106861
info@markelab.com
name
RSPO2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07511
tested applications
ELISA, WB, IP
Description
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | R-spondin 2 homolog (RSPO2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:3000; IP: 1:500-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6UXX9 |
| Gene ID | 340419 |
| Alias | R-spondin-2,Roof plate-specific spondin-2 (hRspo2),RSPO2 |
| Background | Antibody anti-RSPO2 |
| Status | RUO |
| Note | Mol. Weight 33 kDa |
Descripción
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