Anti-Rh Blood Group, D Antigen Antibody (Anti-RHD) Antibody

Este producto es parte de RHD - Rh blood group D antigen
Product Graph
364€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Anti-Rh Blood Group, D Antigen Antibody (Anti-RHD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx239961
tested applications
ELISA, WB, IHC

Description

Anti-Rh Blood Group, D Antigen Antibody (Anti-RHD) Antibody is a Rabbit Polyclonal antibody for the detection of RHD.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Anti-Rh Blood Group, D Antigen Antibody (Anti-RHD)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q02161
Alias
Blood group Rh(D) polypeptide,RH,Rh4,RH30,RhII,RhPI,DIIIc,RHCED,RHDel,RHPII,RhDCw,CD240D,Rh polypeptide 2,Rhesus D antigen
Background
Antibody anti-RHD
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

RHD (Rh blood group D antigen), encoded by the RHD gene, is a major component of the Rh blood group system, one of the most clinically significant blood group systems in humans. The Rh system includes a range of antigens, but the D antigen is the most important for its role in blood transfusion compatibility, pregnancy, and disease. The Rh system is widely recognized in transfusion medicine, where the presence or absence of the D antigen determines whether an individual is classified as Rh-positive (Rh+) or Rh-negative (Rh-). The Rh system, particularly the D antigen, plays a crucial role in immune reactions, alloimmunization, and hemolytic disease of the newborn (HDN). The RHD gene is located on chromosome 1 and is closely linked to the RHCE gene, which encodes other Rh antigens, particularly C and E. The Rh proteins, including the D antigen, are integral membrane proteins that span the cell membrane and play an essential role in the transportation of ions and gases across the cell membrane, especially in erythrocytes (red blood cells). The RHD gene codes for the RhD protein, and its expression is key to determining whether an individual expresses the RhD antigen on the surface of their erythrocytes.

Related Products

FNab10000

RHD antibody

Ver Producto
abx029359

Rh Blood Group D Antigen (RHD) Antibody

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

Ver Producto
abx132208

Rh Blood Group, D Antigen (RHD) Antibody

Rh Blood Group, D Antigen (RHD) Antibody is a Rabbit Polyclonal against Rh Blood Group, D Antigen (RHD).

Ver Producto