KRAS antibody
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935106861
info@markelab.com
name
KRAS antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10239
tested applications
ELISA, WB, IHC, IF
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GTPase KRas (KRAS) |
| Host | Rabbit |
| Reactivity | Human, rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 21 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P01116 |
| Alias | GTPase KRas,K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras,GTPase KRas, N-terminally processed,KRAS,KRAS2,RASK2 |
| Background | Antibody anti-KRAS |
| Status | RUO |
| Note | Mol. Weight 21 kDa |
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Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).
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