RASGRP2 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAS guanyl releasing protein 2(calcium and DAG-regulated) (RASGRP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7LDG7 |
| Gene ID | 10235 |
| Alias | RAS guanyl-releasing protein 2,Calcium and DAG-regulated guanine nucleotide exchange factor I (CalDAG-GEFI),Cdc25-like protein (hCDC25L),F25B3.3 kinase-like protein,RASGRP2,CDC25L,MCG7 |
| Background | Antibody anti-RASGRP2 |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Descripción
Related Products
RASGRP2 antibody
Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Ver Producto
RAS Guanyl Nucleotide-Releasing Protein 2 (RASGRP2) Antibody
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Ver Producto
RAS Guanyl Nucleotide-Releasing Protein 2 (RASGRP2) Antibody
Ras Guanyl Releasing Protein 2 (Calcium And Dag-Regulated) Antibody is a Rabbit Polyclonal antibody against Ras Guanyl Releasing Protein 2 (Calcium And Dag-Regulated).
Ver Producto