RAB2A antibody

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935106861
info@markelab.com
name
RAB2A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07002
tested applications
ELISA, WB, IHC
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | RAB2A, member RAS oncogene family (RAB2A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 24 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P61019 |
Alias | LHX,RAB2,Ras-related protein Rab-2A |
Background | Antibody anti-RAB2A |
Status | RUO |
Note | Mol. Weight 24 kDa |
RAB2A, member RAS oncogene family (RAB2A) is a small GTPase that is part of the RAS superfamily of proteins, which regulate intracellular vesicular trafficking and membrane dynamics RAB2A specifically plays a critical role in the transport of vesicles between the endoplasmic reticulum (ER) and the Golgi apparatus, an essential step in the secretory pathway that is crucial for protein sorting, glycosylation, and secretion Additionally, RAB2A is involved in regulating cell cycle progression, vesicular fusion, and cellular responses to stress Dysregulation of RAB2A can lead to various diseases, including cancer, where abnormal vesicular trafficking and cell proliferation are associated with tumor growth and metastasis Furthermore, alterations in RAB2A’s function are also implicated in neurodegenerative diseases, as defects in intracellular protein transport can disrupt cellular homeostasis and contribute to disease pathogenesis
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