RAB2A antibody

Este producto es parte de RAB - member RAS oncogene family
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935106861
info@markelab.com
name
RAB2A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07002
tested applications
ELISA, WB, IHC

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAB2A, member RAS oncogene family (RAB2A)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
24 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P61019
Alias
LHX,RAB2,Ras-related protein Rab-2A
Background
Antibody anti-RAB2A
Status
RUO
Note
Mol. Weight 24 kDa

RAB2A, member RAS oncogene family (RAB2A) is a small GTPase that is part of the RAS superfamily of proteins, which regulate intracellular vesicular trafficking and membrane dynamics RAB2A specifically plays a critical role in the transport of vesicles between the endoplasmic reticulum (ER) and the Golgi apparatus, an essential step in the secretory pathway that is crucial for protein sorting, glycosylation, and secretion Additionally, RAB2A is involved in regulating cell cycle progression, vesicular fusion, and cellular responses to stress Dysregulation of RAB2A can lead to various diseases, including cancer, where abnormal vesicular trafficking and cell proliferation are associated with tumor growth and metastasis Furthermore, alterations in RAB2A’s function are also implicated in neurodegenerative diseases, as defects in intracellular protein transport can disrupt cellular homeostasis and contribute to disease pathogenesis

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