Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
Primary Antibodies
polyclonal
human,mouse,rat
protein kinase C, gamma
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
78 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
PRKCG
PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14
This product is for research use only.
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Ver másProtein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and ...
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Ver másRabbit polyclonal antibody against PRKCG protein. Immunogen region is C-terminal.
43.75€ (10 µg)
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