IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.
Primary Antibodies
polyclonal
human,rat
interleukin 18(interferon-gamma-inducing factor)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IP, IHC, IF
24 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IP: 1:500-1:5000 ; IHC: 1:50-1:500; IF: 1:10-1:100
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
IL18
IL18,IL-18, IGIF, IL1F4,IL-1F4
This product is for research use only.
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