PARP1 antibody

PARP1 antibody
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Name
PARP1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab06151
Tested Applications
ELISA, WB, IHC, IF

Description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Documentos del producto

Instrucciones
Descargar
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
poly (ADP-ribose) polymerase 1 (PARP1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
115 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P09874
Gene ID
142
Alias
Poly [ADP-ribose] polymerase 1 (PARP-1),ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1),DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1 (ADPRT 1),Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1,Poly [ADP-ribose] polymerase 1, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1, 89-kDa form,Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1, 24-kDa form,Poly [ADP-ribose] polymerase 1, 28-kDa form,PARP1,ADPRT,PPOL
Background
Antibody anti-PARP1
Status
RUO
Note
Mol. Weight 115 kDa

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