SQSTM1 antibody
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935106861
info@markelab.com
name
SQSTM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06086
tested applications
ELISA, WB, IHC, IF
Description
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sequestosome 1 (SQSTM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13501 |
| Gene ID | 8878 |
| Alias | SQSTM1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B, FTDALS3, NADGP, DMRV |
| Background | Antibody anti-SQSTM1 |
| Status | RUO |
| Note | Mol. Weight 65 kDa |
Descripción
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SQSTM1 antibody
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Ver Producto