anti- NUP93 antibody
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Precio
Precio a consultar
Antibody anti-NUP93
proveedor
FineTestreference
FNab05931Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling(PubMed:26878725).
Background
Nucleoporin 93 (NUP93) is another integral component of the nuclear pore complex, playing a critical role in the maintenance and function of the nuclear envelope NUP93 is involved in the structural formation of the nuclear pore and facilitates the transport of molecules, such as RNA and proteins, across the nuclear membrane It participates in the organization of the nuclear pore complex and is essential for the proper function of nucleocytoplasmic transport, ensuring that gene expression and cellular responses are maintained NUP93 also interacts with other nucleoporins to form the scaffold for the central pore and is involved in regulating the selective passage of molecules across the nuclear envelope Dysregulation of NUP93 has been associated with various diseases, including cancers, where defects in nuclear transport contribute to cellular dysfunction, uncontrolled growth, and metastasis Additionally, NUP93 plays a role in cellular signaling and maintaining nuclear integrity under stress conditions, highlighting its importance in preserving cellular homeostasis and response to environmental changes
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
nucleoporin 93kDa
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB
observerd MW
93 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
NUP93
alias
nucleoporin 93kDa, nuclear pore complex protein Nup93
uniprot id
note
This product is for research use only.
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anti- NUP93 antibody
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proveedor
FineTestreference
FNab05931Tested Applications
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polyclonalPlays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and T...
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