anti- NUP93 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
anti- NUP93 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05931
tested applications
ELISA, WB
Description
Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling(PubMed:26878725).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nucleoporin 93kDa |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 93 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N1F7 |
| Gene ID | 9688 |
| Alias | nucleoporin 93kDa, nuclear pore complex protein Nup93 |
| Background | Antibody anti-NUP93 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
Nucleoporin 93 (NUP93) is another integral component of the nuclear pore complex, playing a critical role in the maintenance and function of the nuclear envelope NUP93 is involved in the structural formation of the nuclear pore and facilitates the transport of molecules, such as RNA and proteins, across the nuclear membrane It participates in the organization of the nuclear pore complex and is essential for the proper function of nucleocytoplasmic transport, ensuring that gene expression and cellular responses are maintained NUP93 also interacts with other nucleoporins to form the scaffold for the central pore and is involved in regulating the selective passage of molecules across the nuclear envelope Dysregulation of NUP93 has been associated with various diseases, including cancers, where defects in nuclear transport contribute to cellular dysfunction, uncontrolled growth, and metastasis Additionally, NUP93 plays a role in cellular signaling and maintaining nuclear integrity under stress conditions, highlighting its importance in preserving cellular homeostasis and response to environmental changes
Related Products
anti- NUP93 antibody
Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling(PubMed:26878725).
Ver Producto
Nucleoporin 93 (NUP93) Antibody
NUP93 Antibody is a Rabbit Polyclonal antibody against NUP93.
Ver Producto
Nucleoporin 93 kDa (NUP93) Antibody
Nucleoporin 93 kDa Antibody is a Rabbit Polyclonal antibody against Nucleoporin 93 kDa.
Ver Producto