anti- NUP93 antibody

Este producto es parte de NUP - nucleoporin
anti- NUP93 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-NUP93

proveedor

FineTest

reference

FNab05931

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling(PubMed:26878725).


Background

Nucleoporin 93 (NUP93) is another integral component of the nuclear pore complex, playing a critical role in the maintenance and function of the nuclear envelope NUP93 is involved in the structural formation of the nuclear pore and facilitates the transport of molecules, such as RNA and proteins, across the nuclear membrane It participates in the organization of the nuclear pore complex and is essential for the proper function of nucleocytoplasmic transport, ensuring that gene expression and cellular responses are maintained NUP93 also interacts with other nucleoporins to form the scaffold for the central pore and is involved in regulating the selective passage of molecules across the nuclear envelope Dysregulation of NUP93 has been associated with various diseases, including cancers, where defects in nuclear transport contribute to cellular dysfunction, uncontrolled growth, and metastasis Additionally, NUP93 plays a role in cellular signaling and maintaining nuclear integrity under stress conditions, highlighting its importance in preserving cellular homeostasis and response to environmental changes

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

nucleoporin 93kDa


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

93 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

NUP93


alias

nucleoporin 93kDa, nuclear pore complex protein Nup93


note

This product is for research use only.


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RUO

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