NCF2 antibody
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Description
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | neutrophil cytosolic factor 2 (NCF2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 68 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P19878 |
| Gene ID | 4688 |
| Alias | Neutrophil cytosol factor 2 (NCF-2),67 kDa neutrophil oxidase factor,NADPH oxidase activator 2,Neutrophil NADPH oxidase factor 2,p67-phox,NCF2,NOXA2,P67PHOX |
| Background | Antibody anti-NCF2 |
| Status | RUO |
| Note | Mol. Weight 68 kDa |
Descripción
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