NCAPH antibody
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Description
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | non-SMC condensin I complex, subunit H (NCAPH) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 83kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15003 |
| Gene ID | 23397 |
| Alias | Condensin complex subunit 2,Barren homolog protein 1,Chromosome-associated protein H (hCAP-H),Non-SMC condensin I complex subunit H,XCAP-H homolog,NCAPH,BRRN,BRRN1,CAPH,KIAA0074 |
| Background | Antibody anti-NCAPH |
| Status | RUO |
| Note | Mol. Weight 83 kDa |
Descripción
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NCAPH antibody
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
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Condensin Complex Subunit 2 (NCAPH) Antibody is a Rabbit Polyclonal antibody against Condensin Complex Subunit 2 (NCAPH). This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described.
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