MMP13 antibody
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935106861
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name
MMP13 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05235
tested applications
ELISA, IHC, WB, IF
Description
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13(70 kDa), unglycosylated proform(54 kDa).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | matrix metallopeptidase 13(collagenase 3) (MMP13) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54kd,70kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P45452 |
| Gene ID | 4322 |
| Alias | CLG3,MDST,MANDP1,MMP-13,Collagenase 3 |
| Background | Antibody anti-MMP13 |
| Status | RUO |
| Note | Mol. Weight 54 kDa, 70 kDa |
Descripción
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