MED12 antibody
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Name
MED12 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab05087
Tested Applications
ELISA, WB
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | mediator complex subunit 12 (MED12) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 230 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q93074 |
| Gene ID | 9968 |
| Alias | Mediator of RNA polymerase II transcription subunit 12,Activator-recruited cofactor 240 kDa component (ARC240),CAG repeat protein 45,Mediator complex subunit 12,OPA-containing protein,Thyroid hormone receptor-associated protein complex 230 kDa component (Trap230),Trinucleotide repeat-containing gene 11 protein,MED12,ARC240,CAGH45,HOPA,KIAA0192,TNRC11,TRAP230 |
| Background | Antibody anti-MED12 |
| Status | RUO |
| Note | Mol. Weight 230 kDa |
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