MED12 antibody
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Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mediator complex subunit 12 (MED12) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 230 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q93074 |
| Gene ID | 9968 |
| Alias | Mediator of RNA polymerase II transcription subunit 12,Activator-recruited cofactor 240 kDa component (ARC240),CAG repeat protein 45,Mediator complex subunit 12,OPA-containing protein,Thyroid hormone receptor-associated protein complex 230 kDa component (Trap230),Trinucleotide repeat-containing gene 11 protein,MED12,ARC240,CAGH45,HOPA,KIAA0192,TNRC11,TRAP230 |
| Background | Antibody anti-MED12 |
| Status | RUO |
| Note | Mol. Weight 230 kDa |
Descripción
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