MAGEC2 antibody
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935106861
info@markelab.com
name
MAGEC2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04944
tested applications
ELISA, IHC
Description
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | melanoma antigen family C, 2 (MAGEC2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:20 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 41 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UBF1 |
| Gene ID | 51438 |
| Alias | Melanoma-associated antigen C2,Cancer/testis antigen 10 (CT10),Hepatocellular carcinoma-associated antigen 587,MAGE-C2 antigen,MAGE-E1 antigen,MAGEC2,HCA587,MAGEE1 |
| Background | Antibody anti-MAGEC2 |
| Status | RUO |
| Note | Mol. Weight 41 kDa |
Descripción
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MAGEC2 antibody
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Ver Producto