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Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Primary Antibodies
polyclonal
human
melanoma antigen family C, 2
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC
41 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
IHC: 1:20 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
MAGEC2
Cancer/testis antigen 10, CT10, HCA587, MAGE C2 antigen, MAGE E1 antigen, MAGEC2, MAGEE1, melanoma antigen family C, 2, Melanoma associated antigen C2
This product is for research use only.
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