LRWD1 antibody
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935106861
info@markelab.com
name
LRWD1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04867
tested applications
ELISA, WB
Description
Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | leucine-rich repeats and WD repeat domain containing 1 (LRWD1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 85 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UFC0 |
| Gene ID | 222229 |
| Alias | Leucine-rich repeat and WD repeat-containing protein 1,Centromere protein 33 (CENP-33),Origin recognition complex-associated protein (ORC-associated protein, ORCA),LRWD1,CENP-33,ORCA |
| Background | Antibody anti-LRWD1 |
| Status | RUO |
| Note | Mol. Weight 85 kDa |
Descripción
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