JUN antibody
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Description
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | jun oncogene (JUN) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 39 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P05412 |
| Gene ID | 3725 |
| Alias | Transcription factor Jun,Activator protein 1 (AP1),Proto-oncogene c-Jun,Transcription factor AP-1 subunit Jun,V-jun avian sarcoma virus 17 oncogene homolog,p39,JUN |
| Background | Antibody anti-JUN |
| Status | RUO |
| Note | Mol. Weight 39 kDa |
Descripción
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JUN antibody
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
Ver ProductoJUN antibody
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer(CRC) cells(PubMed:24623306). Binds to the USP28 promoter in colorectal cancer(CRC) cells(PubMed:24623306).
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