IVNS1ABP antibody
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Description
Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines(By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | influenza virus NS1A binding protein (IVNS1ABP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y6Y0 |
| Gene ID | 10625 |
| Alias | Influenza virus NS1A-binding protein (NS1-BP, NS1-binding protein),Aryl hydrocarbon receptor-associated protein 3,Kelch-like protein 39,IVNS1ABP,ARA3,FLARA3,KIAA0850,KLHL39,NS1,NS1BP |
| Background | Antibody anti-IVNS1ABP |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
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