IMPDH1 antibody

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935106861
info@markelab.com
name
IMPDH1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04302
tested applications
ELISA, WB, IHC

Description

Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
IMP(inosine monophosphate) dehydrogenase 1 (IMPDH1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
53-60 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P20839
Gene ID
3614
Alias
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1, IMPD 1, IMPDH 1),IMPDH-I,IMPDH1,IMPD1
Background
Antibody anti-IMPDH1
Status
RUO
Note
Mol. Weight 53-60 kDa

Descripción

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FNab04302

IMPDH1 antibody

Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Ver Producto