IL9 antibody
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935106861
info@markelab.com
name
IL9 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04286
tested applications
ELISA, WB, IHC
Description
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 9 (IL9) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 19 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P15248 |
| Gene ID | 3578 |
| Alias | P40,HP40,IL-9,Cytokine P40,T-cell growth factor P40 |
| Background | Antibody anti-IL9 |
| Status | RUO |
| Note | Mol. Weight 19 kDa |
Descripción
Interleukin-9 (IL9) is a multifunctional cytokine belonging to the type I cytokine family. Originally classified as a T cell growth factor, IL-9 has since been found to influence a variety of immune cells, including T cells, B cells, mast cells, eosinophils, and epithelial cells. Produced predominantly by a subset of CD4+ T cells known as Th9 cells (T helper 9), IL-9 is involved in many immune responses, particularly those related to allergies, asthma, and parasitic infections. The discovery of IL-9’s wide range of biological activities, from promoting inflammation to supporting tissue repair, has highlighted its dual role as both a protective and pathogenic cytokine. This ambivalence makes IL-9 a key player in immune regulation. While it is essential in protective immunity, especially against helminth infections, its dysregulation is implicated in various allergic diseases and autoimmune disorders, making it a target of therapeutic interest.
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