anti- IL1RL2 antibody

Descripción

Receptor for interleukin-36(IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways(By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

interleukin 1 receptor-like 2

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, FC

observerd MW

65 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:1000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

IL1RL2

alias

IL1RL2, IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2, IL-1R6

uniprot id

https://www.uniprot.org/uniprotkb/Q9HB29

gene id

https://www.ncbi.nlm.nih.gov/gene/8808

note

This product is for research use only.

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