IL19 antibody

Este producto es parte de IL19 - interleukin 19
IL19 antibody
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Name
IL19 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab04235
Tested Applications
ELISA, IHC, WB

Documentos del producto

Instrucciones
Descargar
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
interleukin 19 (IL19)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
8C3
Observed MW
22 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9UHD0
Gene ID
29949
Alias
MDA1,NG.1,ZMDA1,IL-10C,Melanoma differentiation-associated protein-like protein
Background
Antibody anti-IL19
Status
RUO
Note
Mol. Weight 22 kDa

Background

Interleukin 19 (IL19) is a member of the IL-10 cytokine family, which includes other related cytokines such as IL-20, IL-22, IL-24, and IL-26. The IL-10 family plays key roles in immune regulation, inflammation, and tissue homeostasis. IL-19 was identified for its ability to influence immune responses and is involved in promoting anti-inflammatory effects and tissue repair processes, while also playing a role in the pathology of certain autoimmune and inflammatory diseases. IL-19 is primarily produced by monocytes, macrophages, keratinocytes, and other epithelial cells in response to pro-inflammatory stimuli such as lipopolysaccharides (LPS), IL-1β, and TNF-α. It is classified as a pro-inflammatory cytokine, but it exhibits immunoregulatory functions, particularly in the context of chronic inflammation. IL-19 acts through the IL-20 receptor complex, which consists of the IL-20R1 and IL-20R2 subunits, and triggers downstream signaling pathways, including the JAK-STAT pathway, to modulate the expression of various inflammatory mediators.

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