anti- IL-19 antibody
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935106861
info@markelab.com
name
anti- IL-19 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04235
tested applications
ELISA, IHC, WB
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 19 |
| Host | Mouse |
| Reactivity | human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 8C3 |
| Observed MW | 22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UHD0 |
| Gene ID | 29949 |
| Alias | MDA1,NG.1,ZMDA1,IL-10C,Melanoma differentiation-associated protein-like protein |
| Background | Antibody anti-IL19 |
| Status | RUO |
| Note | This product is for research use only. |
Interleukin 19 (IL19) is a member of the IL-10 cytokine family, which includes other related cytokines such as IL-20, IL-22, IL-24, and IL-26. The IL-10 family plays key roles in immune regulation, inflammation, and tissue homeostasis. IL-19 was identified for its ability to influence immune responses and is involved in promoting anti-inflammatory effects and tissue repair processes, while also playing a role in the pathology of certain autoimmune and inflammatory diseases. IL-19 is primarily produced by monocytes, macrophages, keratinocytes, and other epithelial cells in response to pro-inflammatory stimuli such as lipopolysaccharides (LPS), IL-1β, and TNF-α. It is classified as a pro-inflammatory cytokine, but it exhibits immunoregulatory functions, particularly in the context of chronic inflammation. IL-19 acts through the IL-20 receptor complex, which consists of the IL-20R1 and IL-20R2 subunits, and triggers downstream signaling pathways, including the JAK-STAT pathway, to modulate the expression of various inflammatory mediators.
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