anti- IL-17F antibody

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Product specifications
Category | Primary Antibodies |
Immunogen Target | interleukin 17F |
Host | Mouse |
Reactivity | human,mouse |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Clone ID | 4C0 |
Observed MW | 40 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Protein A+G purification |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q96PD4 |
Alias | ML1,ML-1,IL17A,CANDF6,IL-17F,Cytokine ML-1 |
Background | Antibody anti-IL17F |
Status | RUO |
Note | This product is for research use only. |
Interleukin-17F (IL17F) is a member of the IL-17 cytokine family, which plays a pivotal role in regulating inflammatory responses and bridging the innate and adaptive immune systems. IL-17F is closely related to IL-17A, the founding member of the family, and shares functional similarities with it. Both IL-17F and IL-17A are secreted primarily by T-helper 17 (Th17) cells, a subset of CD4+ T-cells involved in immunity against extracellular pathogens, especially fungi and bacteria. In addition to Th17 cells, IL-17F can also be produced by other cell types such as natural killer (NK) cells, innate lymphoid cells (ILCs), and neutrophils. IL-17F is implicated in several immune-mediated processes, including the promotion of inflammation in tissues. It is primarily associated with the pathogenesis of autoimmune diseases such as psoriasis, asthma, and inflammatory bowel disease (IBD).
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