IFITM1-Specific antibody
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interferon induced transmembrane protein 1(9-27) (IFITM1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:5000 - 1:50000; IHC: 1:200 - 1:1000; IP: 1:500 - 1:1000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 3C10 |
| Observed MW | 14 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P13164 |
| Alias | Interferon-induced transmembrane protein 1,Dispanin subfamily A member 2a (DSPA2a),Interferon-induced protein 17,Interferon-inducible protein 9-27,Leu-13 antigen,IFITM1,CD225,IFI17 |
| Background | Antibody anti-IFITM1 |
| Status | RUO |
| Note | Mol. Weight 14 kDa |
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Human IFITM1 (Interferon-induced transmembrane protein 1) ELISA Kit
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IFITM1 antibody
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and hepatitis C virus(HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.
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