GZMB antibody
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935106861
info@markelab.com
name
GZMB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03737
tested applications
ELISA, WB, IHC, IF
Description
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | granzyme B (GZMB) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P10144 |
| Gene ID | 3002 |
| Alias | Granzyme B,C11,CTLA-1,Cathepsin G-like 1 (CTSGL1),Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease),Fragmentin-2,Granzyme-2,Human lymphocyte protein (HLP),SECT,T-cell serine protease 1-3E,GZMB,CGL1,CSPB,CTLA1,GRB |
| Background | Antibody anti-GZMB |
| Status | RUO |
| Note | Mol. Weight 33 kDa |
Descripción
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