GH1 antibody
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935106861
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name
GH1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03660
tested applications
ELISA, WB, IHC
Description
GH1, also named as GH and GH-N, belongs to the somatotropin/prolactin family. GH1 plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. This antibody has no cross reaction to CSH1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | growth hormone 1 (GH1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 22kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P01241 |
| Gene ID | 2688 |
| Alias | GH,GH-N,GHB5,GHN,IGHD1A,IGHD1B,IGHD2,hGH-N,Growth hormone 1,Pituitary growth hormone,HGH |
| Background | Antibody anti-GH1 |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Descripción
Growth hormone 1 (Somatotropin) (GH1) is a peptide hormone produced by the anterior pituitary gland that regulates growth, metabolism, and cellular regeneration GH1 plays a central role in stimulating growth during childhood and adolescence by promoting the proliferation and differentiation of chondrocytes in bone tissue, enhancing protein synthesis, and stimulating insulin-like growth factor-1 (IGF-1) production in the liver and peripheral tissues GH1 also regulates carbohydrate and lipid metabolism by enhancing lipolysis, increasing glucose availability, and influencing insulin sensitivity Dysregulation of GH1 production can lead to disorders such as gigantism and acromegaly (overproduction) or growth hormone deficiency, resulting in stunted growth and metabolic imbalances GH1 is also involved in muscle growth, tissue repair, and immune system regulation, highlighting its anabolic and regenerative roles GH1 levels decline with age, contributing to reduced muscle mass and increased fat accumulation, and its therapeutic administration is used to treat growth disorders and promote recovery in catabolic states Its wide-ranging effects on growth, metabolism, and tissue maintenance make GH1 a critical regulator of systemic physiology
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