GPNMB antibody

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935106861
info@markelab.com
name
GPNMB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03586
tested applications
ELISA, IHC, WB
Description
Could be a melanogenic enzyme.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | glycoprotein(transmembrane) nmb (GPNMB) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 68 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q14956 |
Gene ID | 10457 |
Alias | Transmembrane glycoprotein NMB,Hematopoietic growth factor inducible neurokinin-1 type,GPNMB,HGFIN,NMB |
Background | Antibody anti-GPNMB |
Status | RUO |
Note | Mol. Weight 68 kDa |
Descripción
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Transmembrane Glycoprotein NMB (GPNMB) Antibody
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein.GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines.GPNMB may be involved in growth delay and reduction of metastatic potential.Two transcript variants encoding different isoforms have been found for this gene.
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