GADD45GIP1 antibody
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935106861
info@markelab.com
name
GADD45GIP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03296
tested applications
ELISA, WB, IP
Description
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | growth arrest and DNA-damage-inducible, gamma interacting protein 1 (GADD45GIP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25-28kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8TAE8 |
| Gene ID | 90480 |
| Alias | Large ribosomal subunit protein mL64,39S ribosomal protein L59, mitochondrial (MRP-L59),CKII beta-associating protein,CR6-interacting factor 1 (CRIF1),Growth arrest and DNA damage-inducible proteins-interacting protein 1,Papillomavirus L2-interacting nuclear protein 1 (PLINP, PLINP-1),p53-responsive gene 6 protein,GADD45GIP1,MRPL59,PLINP1,PRG6 |
| Background | Antibody anti-GADD45GIP1 |
| Status | RUO |
| Note | Mol. Weight 25-28 kDa |
Descripción
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