FN1 antibody

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935106861
info@markelab.com
name
FN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10458
tested applications
ELISA, WB, IHC
Description
Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | fibronectin 1 (FN1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:200-1:2000; IHC: 1:50-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 220-270 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P02751 |
Gene ID | 2335 |
Alias | Fibronectin (FN),Cold-insoluble globulin (CIG),Anastellin,Ugl-Y1,Ugl-Y2,Ugl-Y3,FN1,FN |
Background | Antibody anti-FN1 |
Status | RUO |
Note | Mol. Weight 220-270 kDa |
Descripción
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