anti- FERMT3 antibody

Este producto es parte de FERMT - FERM domain containing kindlin
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935106861
info@markelab.com
name
anti- FERMT3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03078
tested applications
ELISA, WB, IHC, IF

Description

Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). 

Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
Primary Antibodies
Immunogen Target
fermitin family homolog 3(Drosophila)
Host
Rabbit
Reactivity
human,mouse,rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
72-76kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q86UX7
Gene ID
83706
Alias
URP2,KIND3,MIG-2,MIG2B,URP2SF,UNC112C,Kindlin-3
Background
Antibody anti-FERMT3
Status
RUO
Note
This product is for research use only.

Descripción

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