FERMT1 antibody
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Description
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | fermitin family homolog 1(Drosophila) (FERMT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70-77 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BQL6 |
| Gene ID | 55612 |
| Alias | Fermitin family homolog 1,Kindlerin,Kindlin syndrome protein,Kindlin-1,Unc-112-related protein 1,FERMT1,C20orf42,KIND1,URP1 |
| Background | Antibody anti-FERMT1 |
| Status | RUO |
| Note | Mol. Weight 70-77 kDa |
Descripción
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