anti- FADD antibody

Descripción

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

Fas(TNFRSF6)-associated via death domain

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IHC, WB, IP

observerd MW

26 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

FADD

alias

FADD,GIG3, MORT1,IMD90

uniprot id

https://www.uniprot.org/uniprotkb/Q13158

gene id

https://www.ncbi.nlm.nih.gov/gene/8772

note

This product is for research use only.

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Human FADD(FAS-associated death domain protein) ELISA Kit

proveedor

FineTest

reference

EH8374

reactivity

human

status

RUO

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