This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Primary Antibodies
polyclonal
human,mouse,rat
estrogen receptor 2 (ER beta)
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC, WB
55-60 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ESR2
Erb,ESRB,ODG8,ESTRB,NR3A2,ER-BETA,ESR-BETA,Estrogen receptor beta,Nuclear receptor subfamily 3 group A member 2
This product is for research use only.
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Ver másThis gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors...
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Ver másNuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter...
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