PDIA3 antibody

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935106861
info@markelab.com
name
PDIA3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02858
tested applications
ELISA, WB, IHC, IF, FC, IP

Description

PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
protein disulfide isomerase family A, member 3 (PDIA3)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2400; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
57 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, FC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P30101
Alias
Protein disulfide-isomerase A3,58 kDa glucose-regulated protein,58 kDa microsomal protein (p58),Disulfide isomerase ER-60,Endoplasmic reticulum resident protein 57 (ER protein 57, ERp57),Endoplasmic reticulum resident protein 60 (ER protein 60, ERp60),PDIA3,ERP57,ERP60,GRP58
Background
Antibody anti-PDIA3
Status
RUO
Note
Mol. Weight 57 kDa

Descripción

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