DKC1 antibody
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Name
DKC1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab02400
Tested Applications
ELISA, WB, IHC, IF
Description
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | dyskeratosis congenita 1, dyskerin (DKC1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O60832 |
| Gene ID | 1736 |
| Alias | H/ACA ribonucleoprotein complex subunit DKC1,CBF5 homolog,Dyskerin,Nopp140-associated protein of 57 kDa,Nucleolar protein NAP57,Nucleolar protein family A member 4,snoRNP protein DKC1,DKC1,NOLA4 |
| Background | Antibody anti-DKC1 |
| Status | RUO |
| Note | Mol. Weight 43 kDa |
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