DISC1-long-specific antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
DISC1-long-specific antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab02397
Tested Applications
ELISA, WB, IHC, IF, IP
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | disrupted in schizophrenia 1 (DISC1-long) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NRI5 |
| Alias | DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein |
| Background | Antibody anti-DISC1 |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
Background
Disrupted in schizophrenia 1 (DISC1) is a scaffolding protein with diverse roles in neurodevelopment, synaptic function, and adult neurogenesis. Originally identified in a Scottish family with a high incidence of schizophrenia, DISC1 has since been implicated in several psychiatric disorders, including bipolar disorder and major depression. DISC1 interacts with multiple molecular partners, influencing signaling pathways involved in neuronal proliferation, migration, and axonal growth. Additionally, it regulates mitochondrial function and intracellular trafficking. Dysfunctional DISC1 has been associated with structural brain abnormalities, synaptic deficits, and altered neuronal connectivity, which are common features in neuropsychiatric disorders. The multifaceted roles of DISC1 in cellular processes and its potential as a biomarker or therapeutic target underscore its significance in neuroscience and psychiatry research.
Productos relacionados
Disrupted In Schizophrenia 1 Protein (DISC1) Antibody
DISC1 Antibody is a Rabbit Polyclonal antibody against DISC1. This gene encodes a protein with multiple coiled coil moti…
Ver producto
Disrupted In Schizophrenia 1 Protein (DISC1) Antibody
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria…
Ver producto
Disrupted In Schizophrenia 1 Protein (DISC1) Antibody
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria…
Ver producto