CHRNA10 antibody

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935106861
info@markelab.com
name
CHRNA10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01675
tested applications
ELISA, WB

Description

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
cholinergic receptor, nicotinic, alpha 10 (CHRNA10)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
50-52 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9GZZ6
Gene ID
57053
Alias
Neuronal acetylcholine receptor subunit alpha-10,Nicotinic acetylcholine receptor subunit alpha-10 (NACHR alpha-10),CHRNA10,NACHRA10
Background
Antibody anti-CHRNA10
Status
RUO
Note
Mol. Weight 50-52 kDa

Descripción

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