CHRNA10 antibody

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Description
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | cholinergic receptor, nicotinic, alpha 10 (CHRNA10) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 50-52 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9GZZ6 |
Gene ID | 57053 |
Alias | Neuronal acetylcholine receptor subunit alpha-10,Nicotinic acetylcholine receptor subunit alpha-10 (NACHR alpha-10),CHRNA10,NACHRA10 |
Background | Antibody anti-CHRNA10 |
Status | RUO |
Note | Mol. Weight 50-52 kDa |
Descripción
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