CHMP1B antibody
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935106861
info@markelab.com
name
CHMP1B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01657
tested applications
ELISA, WB, IHC
Description
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | chromatin modifying protein 1B (CHMP1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7LBR1 |
| Gene ID | 57132 |
| Alias | Charged multivesicular body protein 1b,CHMP1.5,Chromatin-modifying protein 1b (CHMP1b),Vacuolar protein sorting-associated protein 46-2 (Vps46-2, hVps46-2),CHMP1B,C18orf2 |
| Background | Antibody anti-CHMP1B |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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CHMP1B antibody
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
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