CD9 antibody
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935106861
info@markelab.com
name
CD9 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01508
tested applications
ELISA, WB, IHC
Description
Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD9 molecule (CD9) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:1000-1:5000; IHC: 1:1000-1:4000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 9H0 |
| Observed MW | 25 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P21926 |
| Gene ID | 928 |
| Alias | MIC3,MRP-1,BTCC-1,DRAP-27,TSPAN29,TSPAN-29,Tetraspanin-29,Motility-related protein,Leukocyte antigen MIC3,Cell growth-inhibiting gene 2 protein,5H9 antigen |
| Background | Antibody anti-CD9 |
| Status | RUO |
| Note | Mol. Weight 25 kDa |
Descripción
CD9 is a member of the tetraspanin superfamily, a group of transmembrane proteins involved in various biological processes, particularly in cell adhesion, migration, proliferation, and signaling. CD9 is ubiquitously expressed on the surface of various cell types, including platelets, leukocytes, epithelial cells, endothelial cells, and germ cells. It plays a critical role in cell-cell interactions, especially in the context of immune responses, reproduction, cancer metastasis, and viral infection. One of the unique features of tetraspanins, including CD9, is their ability to organize membrane microdomains known as tetraspanin-enriched microdomains (TEMs). These microdomains function as platforms that regulate the spatial organization of other membrane proteins such as integrins, growth factor receptors, and co-receptors, thus modulating their signaling activity. CD9, in particular, interacts with several key molecules, including integrins (α6β1, α3β1), epidermal growth factor receptor (EGFR), and immunoglobulin superfamily proteins.
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