CD6 antibody

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935106861
info@markelab.com
name
CD6 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09782
tested applications
ELISA, IHC
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD6 molecule (CD6) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 72 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P30203 |
Alias | TP120,T-cell differentiation antigen CD6,T12 |
Background | Antibody anti-CD6 |
Status | RUO |
Note | Mol. Weight 72 kDa |
CD6 is a type I transmembrane glycoprotein expressed on the surface of T cells, some B cells, and a subset of natural killer (NK) cells. It plays a critical role in the modulation of immune responses, particularly in T-cell activation, differentiation, and immune synapse formation. CD6 is involved in regulating the threshold of T-cell receptor (TCR) signaling and acts as a co-stimulatory receptor that modulates immune responses. CD6 is expressed in the thymus, where it is involved in T-cell development, including positive and negative selection during thymic maturation. In peripheral tissues, CD6 helps facilitate immune responses against pathogens, while maintaining immune tolerance to self-antigens. Dysregulation of CD6 signaling is implicated in a range of immune-related conditions, including autoimmune diseases, inflammatory disorders, and certain types of cancer.
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