PECAM1 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
PECAM1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab01464
Tested Applications
ELISA, WB, IHC
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | platelet/endothelial cell adhesion molecule (PECAM1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:2000-1:6000; IHC: 1:500-1:3000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 2D10 |
| Observed MW | 130 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P16284 |
| Gene ID | 5175 |
| Alias | CD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA' |
| Background | Antibody anti-PECAM1 |
| Status | RUO |
| Note | Mol. Weight 130 kDa |
Background
PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.
Productos relacionados
Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1) Antibody
CD31 Antibody is a Rabbit Polyclonal antibody against CD31. The protein encoded by this gene is found on the surface of …
Ver producto
Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1) Antibody
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein a…
Ver producto
Platelet Endothelial Cell Adhesion Molecule / CD31 (PECAM1) Antibody
Platelet Endothelial Cell Adhesion Molecule / CD31 (PECAM1) Antibody is a Rabbit Polyclonal antibody for the detection o…
Ver producto