Name: anti- Cd2ap antibody
Brand: FineTest
SKU: FNab01455
Availability: OnlineOnly

Descripción

Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.

Características del producto

clonality

polyclonal

reactivity

human,mouse

immunogen target

CD2-associated protein

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IF, IP

observerd MW

70 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

CD2AP

alias

CD2AP, CMS

uniprot id

https://www.uniprot.org/uniprotkb/Q9Y5K6

gene id

https://www.ncbi.nlm.nih.gov/gene/23607

note

This product is for research use only.

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